Retrocyclin RC-101 blocks HIV-1 transmission across cervical mucosa in an Organ Culture

BACKGROUND: Cervical tissue based organ cultures have been used successfully to evaluate microbicides for toxicity and antiviral activity. The antimicrobial peptide retrocyclin RC-101 has been shown to have potent anti-HIV activity in cell culture. OBJECTIVE: To evaluate RC-101 in organ culture for...

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Hlavní autoři: Gupta, Phalguni, Ratner, Deena, Ding, Ming, Patterson, Bruce, Rohan, Lisa C, Reinhart, Todd A., Ayyavoo, Velpandi, Huang, Xioli, Patton, Dorothy L, Ramratnam, Bharat, Cole, Alexander M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404240/
https://ncbi.nlm.nih.gov/pubmed/22592582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e318258b420
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