Pirfenidone inhibits TGF-β1-induced over-expression of collagen type I and heat shock protein 47 in A549 cells

BACKGROUND: Pirfenidone is a novel anti-fibrotic and anti-inflammatory agent that inhibits the progression of fibrosis in animal models and in patients with idiopathic pulmonary fibrosis (IPF). We previously showed that pirfenidone inhibits the over-expression of collagen type I and of heat shock pr...

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Sonraí Bibleagrafaíochta
Main Authors: Hisatomi, Keiko, Mukae, Hiroshi, Sakamoto, Noriho, Ishimatsu, Yuji, Kakugawa, Tomoyuki, Hara, Shintaro, Fujita, Hanako, Nakamichi, Seiko, Oku, Hisashi, Urata, Yoshishige, Kubota, Hiroshi, Nagata, Kazuhiro, Kohno, Shigeru
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2012
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403980/
https://ncbi.nlm.nih.gov/pubmed/22694981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-12-24
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