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Coexpression of human somatostatin receptor-2 (SSTR2) and SSTR3 modulates antiproliferative signaling and apoptosis

BACKGROUND: Somatostatin (SST) via five G(i) coupled receptors namely SSTR1-5 is known to inhibit cell proliferation by cytostatic and cytotoxic mechanisms. Heterodimerization plays a crucial role in modulating the signal transduction pathways of SSTR subtypes. In the present study, we investigated...

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Hlavní autoři: War, Sajad A, Kumar, Ujendra
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403965/
https://ncbi.nlm.nih.gov/pubmed/22651821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-7-5
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