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Variability in detection and quantification of interferon β-1b–induced neutralizing antibodies

BACKGROUND: Interferon-beta (IFNB) therapy for multiple sclerosis can lead to the induction of neutralizing antibodies (NAbs) against IFNB. Various methods are used for detection and quantification of NAbs. METHODS: Blood samples from 125 IFNB-1b–treated patients, which were tested NAb negative or N...

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Bibliografiska uppgifter
Huvudupphovsmän: Hartung, Hans-Peter, Kieseier, Bernd, Goodin, Douglas S, Arnason, Barry GW, Comi, Giancarlo, Cook, Stuart, Filippi, Massimo, Jeffery, Douglas R, Kappos, Ludwig, Bogumil, Timon, Stemper, Brigitte, Sandbrink, Rupert, Nakada, Yukiko, Nakajima, Haruhiko, Schwenke, Susanne, Lehr, Stephan, Heubach, Jürgen, Pohl, Christoph, Reischl, Joachim
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403940/
https://ncbi.nlm.nih.gov/pubmed/22703536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-129
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