Variability in detection and quantification of interferon β-1b–induced neutralizing antibodies

BACKGROUND: Interferon-beta (IFNB) therapy for multiple sclerosis can lead to the induction of neutralizing antibodies (NAbs) against IFNB. Various methods are used for detection and quantification of NAbs. METHODS: Blood samples from 125 IFNB-1b–treated patients, which were tested NAb negative or N...

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Bibliografiske detaljer
Main Authors: Hartung, Hans-Peter, Kieseier, Bernd, Goodin, Douglas S, Arnason, Barry GW, Comi, Giancarlo, Cook, Stuart, Filippi, Massimo, Jeffery, Douglas R, Kappos, Ludwig, Bogumil, Timon, Stemper, Brigitte, Sandbrink, Rupert, Nakada, Yukiko, Nakajima, Haruhiko, Schwenke, Susanne, Lehr, Stephan, Heubach, Jürgen, Pohl, Christoph, Reischl, Joachim
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403940/
https://ncbi.nlm.nih.gov/pubmed/22703536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-129
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