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Expanded Numbers of Circulating Myeloid Dendritic Cells in Patent Human Filarial Infection Reflect Lower CCR1 Expression

APC dysfunction has been postulated to mediate some of the parasite-specific T cell unresponsiveness seen in patent filarial infection. We have shown that live microfilariae of Brugia malayi induce caspase-dependent apoptosis in human monocyte-derived dendritic cells (DCs) in vitro. This study addre...

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Detalhes bibliográficos
Main Authors: Semnani, Roshanak Tolouei, Mahapatra, Lily, Dembele, Benoit, Konate, Siaka, Metenou, Simon, Dolo, Housseini, Coulibaly, Michel E., Soumaoro, Lamine, Coulibaly, Siaka Y., Sanogo, Dramane, Doumbia, Salif Seriba, Diallo, Abdallah A., Traoré, Sekou F., Klion, Amy, Nutman, Thomas B., Mahanty, Siddhartha
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403815/
https://ncbi.nlm.nih.gov/pubmed/20956349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001605
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