Isoform-Specific Toxicity of Mecp2 in Postmitotic Neurons: Suppression of Neurotoxicity by FoxG1

The methyl-CpG binding protein 2 (MeCP2) is a widely expressed protein, the mutations of which cause Rett syndrome. The level of MeCP2 is highest in the brain where it is expressed selectively in mature neurons. Its functions in postmitotic neurons are not known. The MeCP2 gene is alternatively spli...

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Autors principals: Dastidar, Somasish Ghosh, Bardai, Farah H., Ma, Chi, Price, Valerie, Rawat, Varun, Verma, Pragya, Narayanan, Vinodh, D'Mello, Santosh R.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403752/
https://ncbi.nlm.nih.gov/pubmed/22357867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5841-11.2012
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