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Genetic risk sum score comprised of common polygenic variation is associated with body mass index

Genome-wide association studies (GWAS) of body mass index (BMI) using large samples have yielded approximately a dozen robustly associated variants and implicated additional loci. Individually these variants have small effects and in aggregate explain a small proportion of the variance. As a result,...

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Hlavní autoři: Peterson, Roseann E., Maes, Hermine H., Holmans, Peter, Sanders, Alan R., Levinson, Douglas F., Shi, Jianxin, Kendler, Kenneth S., Gejman, Pablo V., Webb, Bradley T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403709/
https://ncbi.nlm.nih.gov/pubmed/21104096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-010-0917-1
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