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Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila

Type II phosphatidylinositol 4-kinase (PI4KII) produces the lipid phosphatidylinositol 4-phosphate (PI4P), a key regulator of membrane trafficking. Here, we generated genetic models of the sole Drosophila melanogaster PI4KII gene. A specific requirement for PI4KII emerged in larval salivary glands....

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Bibliografske podrobnosti
Main Authors: Burgess, Jason, Del Bel, Lauren M., Ma, Cheng-I J., Barylko, Barbara, Polevoy, Gordon, Rollins, Janet, Albanesi, Joseph P., Krämer, Helmut, Brill, Julie A.
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403109/
https://ncbi.nlm.nih.gov/pubmed/22791894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.077644
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