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Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/β-catenin-mediated lung specification in Xenopus

Embryonic development of the respiratory system is regulated by a series of mesenchymal-epithelial interactions that are only partially understood. Mesenchymal FGF and Wnt2/Wnt2b signaling are implicated in specification of mammalian pulmonary progenitors from the ventral foregut endoderm, but their...

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Autores principales: Rankin, Scott A., Gallas, Alyssa L., Neto, Ana, Gómez-Skarmeta, José Luis, Zorn, Aaron M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Company of Biologists 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403107/
https://ncbi.nlm.nih.gov/pubmed/22791896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.078220
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