STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

Multidimensional cancer genome analysis and validation has defined Quaking (QKI), a member of the signal transduction and activation of RNA (STAR) family of RNA-binding proteins, as a novel glioblastoma multiforme (GBM) tumor suppressor. Here, we establish that p53 directly regulates QKI gene expres...

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Detalhes bibliográficos
Main Authors: Chen, An-Jou, Paik, Ji-Hye, Zhang, Hailei, Shukla, Sachet A., Mortensen, Richard, Hu, Jian, Ying, Haoqiang, Hu, Baoli, Hurt, Jessica, Farny, Natalie, Dong, Caroline, Xiao, Yonghong, Wang, Y. Alan, Silver, Pamela A., Chin, Lynda, Vasudevan, Shobha, DePinho, Ronald A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403014/
https://ncbi.nlm.nih.gov/pubmed/22751500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.189001.112
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