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Hypocretin-1 receptors regulate the reinforcing and reward-enhancing effects of cocaine: pharmacological and behavioral genetics evidence

Considerable evidence suggests that transmission at hypocretin-1 (orexin-1) receptors (Hcrt-R1) plays an important role in the reinstatement of extinguished cocaine-seeking behaviors in rodents. However, far less is known about the role for hypocretin transmission in regulating ongoing cocaine-takin...

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Detalhes bibliográficos
Main Authors: Hollander, Jonathan A., Pham, Don, Fowler, Christie D., Kenny, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402880/
https://ncbi.nlm.nih.gov/pubmed/22837742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2012.00047
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