Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions

FUS is an RNA-binding protein that regulates transcription, alternative splicing, and mRNA transport. Aberrations of FUS are causally associated with familial and sporadic ALS/FTLD. We analyzed FUS-mediated transcriptions and alternative splicing events in mouse primary cortical neurons using exon a...

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Main Authors: Ishigaki, Shinsuke, Masuda, Akio, Fujioka, Yusuke, Iguchi, Yohei, Katsuno, Masahisa, Shibata, Akihide, Urano, Fumihiko, Sobue, Gen, Ohno, Kinji
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402842/
https://ncbi.nlm.nih.gov/pubmed/22829983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00529
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