Antidepressant-like effects of ginsenoside Rg1 are due to activation of the BDNF signalling pathway and neurogenesis in the hippocampus

BACKGROUND AND PURPOSE: Ginsenoside Rg1 (Rg1) is one of the major bioactive ingredients of Panax ginseng with little toxicity and has been shown to have neuroprotective effects. In this study, we investigated the antidepressant-like effect of Rg1 in models of depression in mice. EXPERIMENTAL APPROAC...

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Hlavní autoři: Jiang, Bo, Xiong, Zhe, Yang, Jun, Wang, Wei, Wang, Yue, Hu, Zhuang-Li, Wang, Fang, Chen, Jian-Guo
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2012
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402811/
https://ncbi.nlm.nih.gov/pubmed/22335772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01902.x
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