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Imaging biomarkers to monitor response to the hypoxia-activated prodrug TH-302 in the MiaPaCa2 flank xenograft model
TH-302, a hypoxia-activated anticancer prodrug was evaluated for anti-tumor activity and changes in dynamic contrast enhanced (DCE)- and diffusion weighted (DW)-magnetic resonance imaging (MRI) in a mouse model of pancreatic cancer. TH-302 monotherapy resulted in a significant delay in tumor growth...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402593/ https://ncbi.nlm.nih.gov/pubmed/22554971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mri.2012.02.015 |
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