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Increased Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Expression Mediates Intrinsic Airway Smooth Muscle Hypercontractility in Asthma

Rationale: Asthma is characterized by disordered airway physiology as a consequence of increased airway smooth muscle contractility. The underlying cause of this hypercontractility is poorly understood. Objectives: We sought to investigate whether the burden of oxidative stress in airway smooth musc...

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Detalhes bibliográficos
Main Authors: Sutcliffe, Amanda, Hollins, Fay, Gomez, Edith, Saunders, Ruth, Doe, Camille, Cooke, Marcus, Challiss, R. A. John, Brightling, Chris E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402550/
https://ncbi.nlm.nih.gov/pubmed/22108207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201107-1281OC
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