Differential Gene Expression in Tamoxifen-Resistant Breast Cancer Cells Revealed by a New Analytical Model of RNA-Seq Data

Resistance to tamoxifen (Tam), a widely used antagonist of the estrogen receptor (ER), is a common obstacle to successful breast cancer treatment. While adjuvant therapy with Tam has been shown to significantly decrease the rate of disease recurrence and mortality, recurrent disease occurs in one th...

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Detalhes bibliográficos
Main Authors: Huber-Keener, Kathryn J., Liu, Xiuping, Wang, Zhong, Wang, Yaqun, Freeman, Willard, Wu, Song, Planas-Silva, Maricarmen D., Ren, Xingcong, Cheng, Yan, Zhang, Yi, Vrana, Kent, Liu, Chang-Gong, Yang, Jin-Ming, Wu, Rongling
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402532/
https://ncbi.nlm.nih.gov/pubmed/22844461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041333
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