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The T Box Transcription Factor TBX2 Promotes Epithelial-Mesenchymal Transition and Invasion of Normal and Malignant Breast Epithelial Cells

The T box transcription factor TBX2, a master regulator of organogenesis, is aberrantly amplified in aggressive human epithelial cancers. While it has been shown that overexpression of TBX2 can bypass senescence, a failsafe mechanism against cancer, its potential role in tumor invasion has remained...

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Main Authors: Wang, Bin, Lindley, Linsey E., Fernandez-Vega, Virneliz, Rieger, Megan E., Sims, Andrew H., Briegel, Karoline J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402503/
https://ncbi.nlm.nih.gov/pubmed/22844464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041355
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