The Effects of Simvastatin or Interferon-α on Infectivity of Human Norovirus Using a Gnotobiotic Pig Model for the Study of Antivirals

The lack of an animal model for human norovirus (HuNoV) has hindered the development of therapeutic strategies. This study demonstrated that a commonly used cholesterol-lowering statin medication, simvastatin, which increases HuNoV replication in an in vitro replicon system, also enhances HuNoV infe...

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Detaylı Bibliyografya
Asıl Yazarlar: Jung, Kwonil, Wang, Qiuhong, Kim, Yunjeong, Scheuer, Kelly, Zhang, Zhenwen, Shen, Quan, Chang, Kyeong-Ok, Saif, Linda J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402445/
https://ncbi.nlm.nih.gov/pubmed/22911825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041619
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