Amniotic-Fluid–Derived Mesenchymal Stem Cells Overexpressing Interleukin-1 Receptor Antagonist Improve Fulminant Hepatic Failure

Uncontrolled hepatic immunoactivation is regarded as the primary pathological mechanism of fulminant hepatic failure (FHF). The major acute-phase mediators associated with FHF, including IL-1β, IL-6, and TNF-α, impair the regeneration of liver cells and stem cell grafts. Amniotic-fluid–derived mesen...

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Autors principals: Zheng, Yu-Bao, Zhang, Xiao-Hong, Huang, Zhan-Lian, Lin, Chao-Shuang, Lai, Jing, Gu, Yu-Rong, Lin, Bin-Liang, Xie, Dong-Ying, Xie, Shi-Bin, Peng, Liang, Gao, Zhi-Liang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402415/
https://ncbi.nlm.nih.gov/pubmed/22844472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041392
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