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Matrix-M™ Adjuvant Induces Local Recruitment, Activation and Maturation of Central Immune Cells in Absence of Antigen

Saponin-based adjuvants are widely used to enhance humoral and cellular immune responses towards vaccine antigens, although it is not yet completely known how they mediate their stimulatory effects. The aim of this study was to elucidate the mechanism of action of adjuvant Matrix-M™ without antigen...

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Detalhes bibliográficos
Main Authors: Reimer, Jenny M., Karlsson, Karin H., Lövgren-Bengtsson, Karin, Magnusson, Sofia E., Fuentes, Alexis, Stertman, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402407/
https://ncbi.nlm.nih.gov/pubmed/22844480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041451
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