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Methazolamide Is a New Hepatic Insulin Sensitizer That Lowers Blood Glucose In Vivo

We previously used Gene Expression Signature technology to identify methazolamide (MTZ) and related compounds with insulin sensitizing activity in vitro. The effects of these compounds were investigated in diabetic db/db mice, insulin-resistant diet-induced obese (DIO) mice, and rats with streptozot...

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Dettagli Bibliografici
Autori principali: Konstantopoulos, Nicky, Molero, Juan C., McGee, Sean L., Spolding, Briana, Connor, Tim, de Vries, Melissa, Wanyonyi, Stephen, Fahey, Richard, Morrison, Shona, Swinton, Courtney, Jones, Sharon, Cooper, Adrian, Garcia-Guerra, Lucia, Foletta, Victoria C., Krippner, Guy, Andrikopoulos, Sofianos, Walder, Ken R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402314/
https://ncbi.nlm.nih.gov/pubmed/22586591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0578
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