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Attenuation of oxidative stress, inflammation and apoptosis by minocycline prevents retrovirus-induced neurodegeneration in mice

The ts1 mutant of the Moloney murine leukemia virus (MoMuLV) causes neurodegeneration in infected mice that resembles HIV-associated dementia. We have shown previously that ts1 infects glial cells in the brain, but not neurons. The most likely mechanism for ts1-mediated neurodegeneration is loss of...

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Detalhes bibliográficos
Main Authors: Kuang, Xianghong, Scofield, Virginia L., Yan, Mingshan, Stoica, George, Liu, Na, Wong, Paul K.Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402231/
https://ncbi.nlm.nih.gov/pubmed/19523933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.06.007
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