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Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens

This review summarizes recent evidence from knock-out mice on the role of reactive oxygen intermediates and reactive nitrogen intermediates (RNI) in mammalian immunity. Reflections on redundancy in immunity help explain an apparent paradox: the phagocyte oxidase and inducible nitric oxide synthase a...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Nathan, Carl, Shiloh, Michael U.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2000
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34021/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10922044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.16.8841
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