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Loss in CD4 T-cell responses to multiple epitopes in influenza due to expression of one additional MHC class II molecule in the host

An understanding of factors controlling CD4 T-cell immunodominance is needed to pursue CD4 T-cell epitope-driven vaccine design, yet our understanding of this in humans is limited by the complexity of potential MHC class II molecule expression. In the studies described here, we took advantage of gen...

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Détails bibliographiques
Auteurs principaux: Nayak, Jennifer L, Sant, Andrea J
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401981/
https://ncbi.nlm.nih.gov/pubmed/22747522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03599.x
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