Functional Impact of Sequence Alterations Found in BRCA1 Promoter/5'UTR Region in Breast/Ovarian Cancer Families from Upper Silesia, Poland

The 5' region of BRCA1 contains multiple regulatory sequences flanking the two alternative promoters α and β and two alternative, non-coding exons, 1a and 1b. Aberrations within the 5' region BRCA1 (encompassing two alternative promoters α and β and exons 1a and 1b) may be associated with...

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Bibliographische Detailangaben
Hauptverfasser: Pamuła, Jolanta, Krześniak, Małgorzata, Zientek, Helena, Pękala, Wioletta, Rusin, Marek, Grzybowska, Ewa
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2006
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401915/
https://ncbi.nlm.nih.gov/pubmed/20222999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-4-1-20
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