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Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming

Pulmonary arterial hypertension (PAH) is a progressive and fatal disease of the lung vasculature for which the molecular etiologies are unclear. Specific metabolic alterations have been identified in animal models and in PAH patients, though existing data focus mainly on abnormalities of glucose hom...

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Библиографические подробности
Главные авторы: Fessel, Joshua P., Hamid, Rizwan, Wittmann, Bryan M., Robinson, Linda J., Blackwell, Tom, Tada, Yuji, Tanabe, Nobuhiro, Tatsumi, Koichiro, Hemnes, Anna R., West, James D.
Формат: Artigo
Язык:Inglês
Опубликовано: Medknow Publications & Media Pvt Ltd 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401874/
https://ncbi.nlm.nih.gov/pubmed/22837861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-8932.97606
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