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Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming
Pulmonary arterial hypertension (PAH) is a progressive and fatal disease of the lung vasculature for which the molecular etiologies are unclear. Specific metabolic alterations have been identified in animal models and in PAH patients, though existing data focus mainly on abnormalities of glucose hom...
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Главные авторы: | , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Medknow Publications & Media Pvt Ltd
2012
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Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401874/ https://ncbi.nlm.nih.gov/pubmed/22837861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-8932.97606 |
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