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On the Discovery, Biological Effects, and Use of Cisplatin and Metallocenes in Anticancer Chemotherapy

The purpose of this paper is to summarize mode of action of cisplatin on the tumor cells, a brief outlook on the metallocene compounds as antitumor drugs as well as the future tendencies for the use of the latter in anticancer chemotherapy. Molecular mechanisms of cisplatin interaction with DNA, DNA...

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Detalhes bibliográficos
Main Authors: Gómez-Ruiz, Santiago, Maksimović-Ivanić, Danijela, Mijatović, Sanja, Kaluđerović, Goran N.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401524/
https://ncbi.nlm.nih.gov/pubmed/22844263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/140284
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