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Real-time single-molecule tethered particle motion experiments reveal the kinetics and mechanisms of Cre-mediated site-specific recombination

Tyrosine family recombinases (YRs) are widely utilized in genome engineering systems because they can easily direct DNA rearrangement. Cre recombinases, one of the most commonly used types of YRs, catalyze site-specific recombination between two loxP sites without the need for high-energy cofactors,...

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Dettagli Bibliografici
Autore principale: Fan, Hsiu-Fang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401459/
https://ncbi.nlm.nih.gov/pubmed/22467208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks274
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