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Factors Influencing the DNA Nuclease Activity of Iron, Cobalt, Nickel, and Copper Chelates

A library of complexes that included iron, cobalt, nickel, and copper chelates of cyclam, cyclen, DOTA, DTPA, EDTA, tripeptide GGH, tetrapeptide KGHK, NTA, and TACN was evaluated for DNA nuclease activity, ascorbate consumption, superoxide and hydroxyl radical generation, and reduction potential und...

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Bibliographic Details
Main Authors: Joyner, Jeff C., Reichfield, Jared, Cowan, J. A.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401417/
https://ncbi.nlm.nih.gov/pubmed/21815680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2052599
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