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Formation of duodenal atresias in Fibroblast growth factor receptor 2IIIb-/- mouse embryos occurs in the absence of an endodermal plug

PURPOSE: Duodenal atresia in humans has been hypothesized to arise from a failure of the duodenal lumen to recanalize after formation of an endodermal plug. Recently, mutations in the Fibroblast Growth Factor Receptor 2 gene have been shown to cause atretic defects of the duodenum in mice (Fgfr2IIIb...

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Detalhes bibliográficos
Main Authors: Botham, Robert, Franco, Marta, Reeder, Amy, Lopukhin, Anastasia, Shiota, Kohei, Yamada, Shigehito, Nichol, Peter F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401378/
https://ncbi.nlm.nih.gov/pubmed/22813799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2012.02.001
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