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Antidepressant effects of Fibroblast Growth Factor-2 in behavioral and cellular models of depression

BACKGROUND: Basic and clinical studies report that the expression of Fibroblast Growth Factor-2 (FGF2) is decreased in the Prefrontal Cortex (PFC) of depressed subjects or rodents exposed to stress, and increased following antidepressant treatment. Here, we aim to determine if: 1) FGF2/FGF receptor...

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Detalhes bibliográficos
Main Authors: Elsayed, Maha, Banasr, Mounira, Duric, Vanja, Fournier, Neil M., Licznerski, Pawel, Duman, Ronald S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401338/
https://ncbi.nlm.nih.gov/pubmed/22513055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.03.003
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