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SPIRONOLACTONE PREVENTS CHLORTHALIDONE-INDUCED SYMPATHETIC ACTIVATION AND INSULIN RESISTANCE IN HYPERTENSIVE PATIENTS

Recent studies from our laboratory indicate that chlorthalidone triggers persistent activation of the sympathetic nervous system and promotes insulin resistance in hypertensive patients, independent of serum potassium. Mechanisms underlying these adverse effects of chlorthalidone remain unknown but...

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Autors principals: Raheja, Prafull, Price, Angela, Wang, Zhongyun, Arbique, Debbie, Adams-Huet, Beverley, Auchus, Richard J., Vongpatanasin, Wanpen
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401321/
https://ncbi.nlm.nih.gov/pubmed/22733474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.194787
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