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SPIRONOLACTONE PREVENTS CHLORTHALIDONE-INDUCED SYMPATHETIC ACTIVATION AND INSULIN RESISTANCE IN HYPERTENSIVE PATIENTS

Recent studies from our laboratory indicate that chlorthalidone triggers persistent activation of the sympathetic nervous system and promotes insulin resistance in hypertensive patients, independent of serum potassium. Mechanisms underlying these adverse effects of chlorthalidone remain unknown but...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Raheja, Prafull, Price, Angela, Wang, Zhongyun, Arbique, Debbie, Adams-Huet, Beverley, Auchus, Richard J., Vongpatanasin, Wanpen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401321/
https://ncbi.nlm.nih.gov/pubmed/22733474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.194787
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