SPIRONOLACTONE PREVENTS CHLORTHALIDONE-INDUCED SYMPATHETIC ACTIVATION AND INSULIN RESISTANCE IN HYPERTENSIVE PATIENTS

Recent studies from our laboratory indicate that chlorthalidone triggers persistent activation of the sympathetic nervous system and promotes insulin resistance in hypertensive patients, independent of serum potassium. Mechanisms underlying these adverse effects of chlorthalidone remain unknown but...

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Main Authors: Raheja, Prafull, Price, Angela, Wang, Zhongyun, Arbique, Debbie, Adams-Huet, Beverley, Auchus, Richard J., Vongpatanasin, Wanpen
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401321/
https://ncbi.nlm.nih.gov/pubmed/22733474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.194787
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