A phage tubulin assembles dynamic filaments by a novel mechanism to center viral DNA within the host cell

Tubulins are essential for the reproduction of many eukaryotic viruses, but historically bacteriophage were assumed not to require a cytoskeleton. Here we identify a tubulin-like protein, PhuZ, from bacteriophage 201φ2-1 and show that it forms filaments in vivo and in vitro. The PhuZ structure has a...

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Main Authors: Kraemer, James A, Erb, Marcella L, Waddling, Christopher A, Montabana, Elizabeth A, Zehr, Elena A, Wang, Hannah, Nguyen, Katrina, Pham, Duy Stephen L, Agard, David A, Pogliano, Joe
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401054/
https://ncbi.nlm.nih.gov/pubmed/22726436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.04.034
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