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Near Infrared Theranostic Photoimmunotherapy (PIT): Repeated Exposure of Light Enhances the Effect of Immunoconjugate

Armed antibody-based targeted molecular therapies offer the possibility of effective tumor control with a minimum of side effects. Photoimmunotherapy (PIT) employs a monoclonal antibody-phototoxic phthalocyanine dye, IR700 conjugate that is activated by focal near infrared (NIR) light irradiation af...

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Detalhes bibliográficos
Main Authors: Mitsuanga, Makoto, Nakajima, Takahito, Sano, Kohei, Choyke, Peter L., Kobayashi, Hisataka
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401044/
https://ncbi.nlm.nih.gov/pubmed/22369484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200648m
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