PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts

Cytokine signaling via various transcription factors regulates receptor activator of nuclear factor (NF)–κB ligand (RANKL)–mediated osteoclast differentiation from monocyte/macrophage lineage cells involved in propagation and resolution of inflammatory bone destruction. Protein inhibitor of activate...

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Main Authors: Hikata, Tomohiro, Takaishi, Hironari, Takito, Jiro, Hakozaki, Akihiro, Furukawa, Mitsuru, Uchikawa, Shinichi, Kimura, Tokuhiro, Okada, Yasunori, Matsumoto, Masahito, Yoshimura, Akihiko, Nishimura, Riko, Reddy, Sakamuri V., Asahara, Hiroshi, Toyama, Yoshiaki
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Hematopoiesis and Stem Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401028/
https://ncbi.nlm.nih.gov/pubmed/18952894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-162594
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