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Depo-Provera abrogates attenuated lentivirus-induced protection in male rhesus macaques challenged intravenously with pathogenic SIVmac239

BACKGROUND: Progesterone administration prior to intravaginal challenge with pathogenic SIVmac239 decreases the protective efficacy of live attenuated vaccines in rhesus macaques. METHODS: To determine if progesterone alters the efficacy of live attenuated vaccines through local or systemic effects,...

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Hlavní autoři: Genescà, Meritxell, Li, Jun, Fritts, Linda, Chohan, Paul, Bost, Kristen, Rourke, Tracy, Blozis, Shelley A., McChesney, Michael B., Miller, Christopher J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401015/
https://ncbi.nlm.nih.gov/pubmed/17669215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0684.2007.00244.x
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