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Thinking Outside the Cleft to Understand Synaptic Activity: Contribution of the Cystine-Glutamate Antiporter (System x(c)(−)) to Normal and Pathological Glutamatergic Signaling

System x(c)(−) represents an intriguing target in attempts to understand the pathological states of the central nervous system. Also called a cystine-glutamate antiporter, system x(c)(−) typically functions by exchanging one molecule of extracellular cystine for one molecule of intracellular glutama...

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Detalhes bibliográficos
Main Authors: Bridges, Richard, Lutgen, Victoria, Lobner, Doug, Baker, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400835/
https://ncbi.nlm.nih.gov/pubmed/22759795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.110.003889
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