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An evolutionary history of the selectin gene cluster in humans

Molecules involved in leukocyte trafficking have a central role in the development of inflammatory and immune responses. We performed F(ST) analysis of the selectin cluster, as well as of SELPLG, ICAM1 and VCAM1. Peaks of significantly high population genetic differentiation were restricted to two r...

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Detalhes bibliográficos
Main Authors: Fumagalli, M, Fracassetti, M, Cagliani, R, Forni, D, Pozzoli, U, Comi, G P, Marini, F, Bresolin, N, Clerici, M, Sironi, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400748/
https://ncbi.nlm.nih.gov/pubmed/22549518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2012.20
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