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A Novel Source of Methylglyoxal and Glyoxal in Retina: Implications for Age-Related Macular Degeneration
Aging of retinal pigment epithelial (RPE) cells of the eye is marked by accumulations of bisretinoid fluorophores; two of the compounds within this lipofuscin mixture are A2E and all-trans-retinal dimer. These pigments are implicated in pathological mechanisms involved in some vision-threatening dis...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3400616/ https://ncbi.nlm.nih.gov/pubmed/22829938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041309 |
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