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Identification of Catalytic Residues Using a Novel Feature that Integrates the Microenvironment and Geometrical Location Properties of Residues

Enzymes play a fundamental role in almost all biological processes and identification of catalytic residues is a crucial step for deciphering the biological functions and understanding the underlying catalytic mechanisms. In this work, we developed a novel structural feature called MEDscore to ident...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Han, Lei, Zhang, Yong-Jun, Song, Jiangning, Liu, Ming S., Zhang, Ziding
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400608/
https://ncbi.nlm.nih.gov/pubmed/22829945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041370
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