Serine Protease Inhibitor Attenuates Ovalbumin Induced Inflammation in Mouse Model of Allergic Airway Disease

BACKGROUND: Serine proteases promote inflammation and tissue remodeling by activating proteinase-activated receptors, urokinase, metalloproteinases and angiotensin. In the present study, 4-(2-Aminoethyl) benzenesulfonyl fluoride (AEBSF) a serine protease inhibitor was evaluated for prophylactic and...

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Bibliographic Details
Main Authors: Saw, Sanjay, Kale, Sagar Laxman, Arora, Naveen
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400607/
https://ncbi.nlm.nih.gov/pubmed/22829914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041107
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