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Evidence from Chlamydomonas on the photoactivation of rhodopsins without isomerization of their chromophore

Attachment of retinal to opsin forms the chromophore N-retinylidene which isomerizes during photoactivation of rhodopsins. To test whether isomerization is crucial, custom-tailored chromophores lacking the β-ionone ring and any isomerizable bonds were incorporated in vivo into the opsin of a blind m...

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Detalhes bibliográficos
Main Authors: Foster, Kenneth W., Saranak, Jureepan, Krane, Sonja, Johnson, Randy L., Nakanishi, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400536/
https://ncbi.nlm.nih.gov/pubmed/21700209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.04.009
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