Intravenous Delivery of the Plasma Fraction of Stored Packed Red Blood Cells Promotes Pancreatic Cancer Growth in Immunocompetent Mice

BACKGROUND: Perioperative blood transfusion in pancreatic cancer patients is linked to decreased survival; however, a causal mechanism has not been determined. During processing and storage of packed red blood cells (pRBCs) biologically active molecules accumulate in the acellular plasma fraction; t...

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Autores principales: Barnett, Carlton C., Beck, Adam W., Holloway, Shane E., Kehler, Marguerite, Schluterman, Marie K., Brekken, Rolf A., Fleming, Jason B., Silliman, Christopher C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400465/
https://ncbi.nlm.nih.gov/pubmed/20564095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25140
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