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Ischemia-Induced Increase in Microvascular Phosphodiesterase 4D Expression in Rat Hippocampus Associated with Blood Brain Barrier Permeability: Effect of Age

[Image: see text] Phosphodiesterase 4D (PDE4D) is one of 16 PDEs expressed in cerebral microvessels, and may be involved in regulating blood-brain barrier (BBB) permeability. To assess the possible role of PDE4D in stroke-related injury in young versus aged rats, we measured microvascular PDE4D expr...

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Hlavní autoři: He, Zhen, He, Bei, Behrle, Brian L, Fejleh, M. Phillip C., Cui, Li, Paule, Merle G., Greenfield, L. John
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2012
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400376/
https://ncbi.nlm.nih.gov/pubmed/22860212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn2001156
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