Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: production process, content and identification of active components

BACKGROUND AIMS: The clinical use of human mesenchymal stromal cells (MSC) requires ex vivo expansion in media containing supplements such as fetal bovine serum or, alternatively, human platelet lysate (PL). METHODS: Platelet concentrates were frozen, quarantine stored, thawed and sterile filtered t...

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Hlavní autoři: Fekete, Natalie, Gadelorge, Mélanie, Fürst, Daniel, Maurer, Caroline, Dausend, Julia, Fleury-Cappellesso, Sandrine, Mailänder, Volker, Lotfi, Ramin, Ignatius, Anita, Sensebé, Luc, Bourin, Philippe, Schrezenmeier, Hubert, Rojewski, Markus Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Informa Healthcare 2012
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400099/
https://ncbi.nlm.nih.gov/pubmed/22296115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14653249.2012.655420
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