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Sunitinib in combination with paclitaxel plus carboplatin in patients with advanced solid tumors: phase I study results

PURPOSE: To evaluate the maximum tolerated dose (MTD), safety, and antitumor activity of sunitinib combined with paclitaxel and carboplatin. METHODS: Successive cohorts of patients with advanced solid tumors received oral sunitinib (25, 37.5, or 50 mg) for 2 consecutive weeks of a 3-week cycle (Sche...

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Detalhes bibliográficos
Main Authors: Heath, Elisabeth I., Blumenschein, George R., Cohen, Roger B., LoRusso, Patricia M., LoConte, Noelle K., Kim, Sindy T., Ruiz-Garcia, Ana, Chao, Richard C., Wilding, George
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400085/
https://ncbi.nlm.nih.gov/pubmed/21140147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1536-1
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