MicroRNA-191 triggers keratinocytes senescence by SATB1 and CDK6 downregulation

Keratinocyte replicative senescence has an important role in time-dependent changes of the epidermis, a tissue with high turnover. Senescence encompasses growth arrest during which cells remain metabolically active but acquire a typical enlarged, vacuolar and flattened morphology. It is also accompa...

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Hlavní autoři: Lena, A.M., Mancini, M., Rivetti di Val Cervo, P., Saintigny, G., Mahé, C., Melino, G., Candi, E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Academic Press 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400053/
https://ncbi.nlm.nih.gov/pubmed/22683624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.05.153
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