Pentoxifylline improves liver regeneration through down-regulation of TNF-α synthesis and TGF-β1 gene expression

AIM: To investigate the mechanism of pentoxifylline (PTX) improvement in liver regeneration. RESULTS: Rats were randomized into 4 groups: Control rats; Sham - sham-operation rats; Saline - 70% hepatectomy plus saline solution; PTX - 70% hepatectomy plus PTX. At 2 and 6 h after hepatectomy, aspartate...

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Detalhes bibliográficos
Main Authors: Martino, Rodrigo Bronze, Coelho, Ana Maria Mendonça, Kubrusly, Márcia Saldanha, Leitão, Regina, Sampietre, Sandra Nassa, Machado, Marcel Cerqueira Cesar, Bacchella, Telesforo, D’Albuquerque, Luiz Augusto Carneiro
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2012
Assuntos:
Brief Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400043/
https://ncbi.nlm.nih.gov/pubmed/22816029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4240/wjgs.v4.i6.146
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