Development and Validation of a High Throughput System for Discovery of Antigens for Autoantibody Detection

An assay employing a panel of tumor-associated antigens has been validated and is available commercially (EarlyCDT®-Lung) to aid the early detection of lung cancer by measurement of serum autoantibodies. The high throughput (HTP) strategy described herein was pursued to identify new antigens to add...

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Bibliographic Details
Main Authors: Macdonald, Isabel K., Allen, Jared, Murray, Andrea, Parsy-Kowalska, Celine B., Healey, Graham F., Chapman, Caroline J., Sewell, Herbert F., Robertson, John F. R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399887/
https://ncbi.nlm.nih.gov/pubmed/22815807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040759
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