Pak1 Regulates the Orientation of Apical Polarization and Lumen Formation by Distinct Pathways

The development of the basic architecture of branching tubules enclosing a central lumen that characterizes most epithelial organs crucially depends on the apico-basolateral polarization of epithelial cells. Signals from the extracellular matrix control the orientation of the apical surface, so that...

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Bibliografiske detaljer
Main Authors: deLeon, Orlando, Puglise, Jason M., Liu, Fengming, Smits, Jos, ter Beest, Martin B., Zegers, Mirjam M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399788/
https://ncbi.nlm.nih.gov/pubmed/22815903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041039
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